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Miniopterus Bat coronavirus HKU8
Miniopterus Bat coronavirus HKU8 is a novel enveloped, single-stranded positive-sense RNA virus species in the Alphacoronavirus genus with a corona-like morphology. It causes severe acute respiratory syndrome in bats. Isolates have not been found in humans.
== Genome ==
The coronaviruses are among the largest RNA viruses, with complex polyadenylated genomes of 26–32 kb, and are divided into four genera: alpha, beta, gamma, and deltacoronaviruses.〔Chu DK, Poon LL, Chan KH, Chen H, Guan Y, Yuen KY, Peiris JS..Coronaviruses in bent-winged bats (Miniopterus spp.). J Gen Virol. 2006 Sep;87(Pt 9):2461-6.〕 The Alpha and betacoronaviruses are derived from the bat gene pool. There are at least four different, but closely related, Alphacoronaviruses (bat-CoV 1A, 1B, HKU7 and HKU8) circulating in bent-winged bats. Coronaviruses in bats are descended from a common ancestor and have been evolving in bats over a long period of time.〔Chu DK, Peiris JS, Chen H, Guan Y, Poon LL. Genomic characterizations of bat coronaviruses (1A, 1B and HKU8) and evidence for co-infections in Miniopterus bats..J Gen Virol. 2008 May;89(Pt 5):1282-7. doi: 10.1099/vir.0.83605-0.〕
A significant percentage of newly emerging viruses are RNA viruses. It is believed this is due to the fact that RNA viruses have a much higher nucleotide mutation rate than DNA viruses.〔Chu, David K.W.,Peiris, J.S. Malik, and Poon, Leo, L.M. Novel Coronaviruses and Astroviruses in Bats. Virologica Sinica. April 2009, 24(2): 100-104.〕
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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